13 Common Questions About CBD Oil

By Jared Kaufman

What is CBD?

Cannabidiol, or CBD, as it is more commonly referred to is a compound found in cannabis and hemp plants. Over the past several years, this compound has made a huge impact on individual’s health and wellness. Thanks to recent research we now know that CBD has a wide variety of health benefits and can potentially help manage and mitigate a multitude of medical conditions.  It is usually found in oil form.

Is CBD safe?

CBD from a reputable brand is safe to use. While CBD is generally considered free from side effects some can exist.  The most common side effects are typically caused by ingesting too much CBD oil and include; drowsiness, nausea, and diarrhea. Similar to any supplement or medication you should always consult a physician prior to use.

Is CBD Legal?

It can depend on who you ask and how your CBD oil is derived.  So much of CBD regulation is tied to marijuana legislation. If you live within a state where marijuana is legal either recreationally or medicinally then you should have nothing to worry about.  The laws are changing fairly quickly and with CBD’s ease of availability online the lack of regulations for the non-psychoactive compound leaves it in a bit of a gray area.

If I Take CBD Will I Fail A Drug Test?

If you may be subjected to a drug test you’re encouraged to exercise caution when taking CBD oil. Some CBD oils especially full spectrum CBD oils may have higher trace amounts of THC, that may cause you to fail a drug test even if you don’t experience a high. Most drug tests are not geared toward identifying CBD. 

Does CBD interact with other medications?

CBD inhibits the cytochrome P450 enzyme, which is involved in metabolization of many drugs. Similar compounds exist in grapefruit that inhibit the same enzyme group. This is why physicians advise patients not to eat grapefruit shortly before or after taking a medication. By inhibiting cytochrome P450, CBD can either reduce or increase the effects of other drugs.  Even though CBD is generally thought of to be safe it is always recommended to consult your physician prior to starting or stopping any new supplements or medication. 

How do I know what dose of CBD I should take?

CBD dosing is not a one-size-fits-all method.  Everyone’s body metabolizes CBD differently so it is recommended to start with a small dose.  Most CBD products have a recommended serving size on the label. It’s recommended to follow the products instructions and perhaps be even more conservative when just starting out. 

Will CBD Get Me High?

This is the most common question people ask about CBD. CBD alone does not contain any psychoactive component that is associated with marijuana or THC. Therefore, you will not get the feeling of being intoxicated from CBD oil. Most hemp used in the making of CBD oil has a maximum of 0.3 percent THC to produce 99 percent pure CBD.

How Do I Take CBD?

The most common form of CBD is in oil form, however, CBD isolate is a powder or crystal. CBD has been added to so many products there are a variety to choose from.  

The most common forms of CBD:

  • Tincture (Sublingual oil drops)

  • CBD Capsules

  • CBD Edibles

  • CBD Vape

  • CBD Topicals (Lotions, Salves, Balms)

What Does CBD Help With?

More and more research into the benefits of CBD is being performed everyday. Recent research shows that CBD oil may help to treat several ailments. The most common of which are; anxiety, asthma, epilepsy, inflammation, insomnia, bipolar disorder, Alzheimer’s disease, chronic pain and more.

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9 Reasons You Should be Using CBD Bath Bombs

Have you ever wanted an at-home spa? CBD bath bombs are your all-in-one solution, providing ultimate relaxation and relief from physical tension, topped by a colorful blast of aromatic fizziness.

If you’ve never seen bath bombs before, they are small “bombs” that burst into a scene of fizziness when dropped into water. Often they contain essential oils and other agents which provide a plethora of benefits and an all-around body-pampering experience.

How Do CBD Bath Bombs Work?

A unique combination of baking soda (sodium bicarbonate), citric acid, Epsom salts (magnesium sulfate), and natural, organic coloring produce the iconic fizziness brought on by bath bombs. Typically bath bombs will contain additives such as essential oils that double as aromatherapy agents, and nourishers that work directly on the skin. Together with the hot water of a bath, your body will feel about as close to a spa-like experience as you can get in a simple bath, but in the comfort of your own home, and for a cheaper price.

In the case of CBD bath bombs, the non-psychoactive cannabis constituent cannabidiol (CBD) is one of the additives placed in the product. CBD has remarkable healing properties, ranging from anxiolytic properties to powerful pain relief.

CBD is typically taken orally, smoked/vaporized, or applied topically, but bath bombs present a new method of ingestion: absorption through opened pores as a result of the heat of the bath.

This allows the CBD to reach the blood stream more rapidly than topical applications, and more importantly penetrate the skin throughout the entire body, rather than a small area.


Below are some of  the reasons you should use CBD bath bombs.


1. Spa-like Environment

With the right atmosphere, a CBD bath bomb can make a bathtub indifferent from a spa. Get the lighting right, play some calming music, and set the water to just the right temperature, and the experience provides an all natural, low cost, and at home spa experience.

This is only the beginning, though. Once the CBD begins to enter the bloodstream in significant proportions after a few minutes of soaking, the effects will compound. You’ll be met with an astounding relaxation, and perhaps a touch of visionary euphoria. The experience could even have spiritual undertones as a result of the meditative state of mind you’ll be in. This mood is induced by the bath and bomb itself and amplified by the CBD.


2. Epsom salt and CBD Work Together

Epsom salt has a very remarkable property to it – it has the capability to draw out harmful toxins from your body and restore balance. In fact, for over 400 years, Epsom salt has been used in “salt detoxes”, which are believed to help not only with toxin removal, but also:

  • Weight/appetite management

  • Sore muscle relief

  • Mood stabilization

  • Overall health improvement

As you can see, there is a significant overlap with CBD, which is touted for its ability to stabilize appetite, provide pain relief, and improve mood. Thus Epsom salt, when used in tandem with CBD, see mutual benefit that you can take advantage of today.


3. Relaxation

CBD is a very potent relaxation inducer and stress reliever. As the saying goes, stress kills, and this is not an exaggeration. To many, CBD is more effective than prescription drugs such as benzodiazepines including Xanax at relieving anxiety, and it far more healthier being non-addictive.

Cannabidiol’s main mechanism of action is on the endocannabinoid system, which is responsible primarily for regularization of several bodily mechanisms. Mood, appetite, libido, and more are controlled by the endocannabinoid system. Inside the body, neurotransmitters known as cannabinoids interact with the system to induce action.

CBD interacts with the system in a light way, so as to induce some of the stabilizing effects that internal cannabinoids (called endocannabinoids) do.

CBD also interacts with many other neural systems, such as:

  • Serotonin (the “happiness” hormone)

  • Dopamine (the reward chemical)

  • GABA (inhibition and relaxation)

  • The hippocampus, which controls emotion and memory


4. Glow

When people speak of bath bombs, you’ll often hear about “the glow”. This refers to the process of the hot water and Epsom salt increasing blood flow and opening pores, resulting in a distinctive bodily glow.

The opening of pores allows toxins to flow out into the Epsom salt, and CBD and essential oils to flow into the skin. The radiating and noticeable difference in skin contrast after getting in water touched by a CBD bath bomb is a precursor to the benefits you’ll be feeling within minutes – relaxation, sore muscle and tension relief, and mood improvement.


5. Benefits of CBD – Soothe Body Aches

CBD has long been touted for its ability to 1) reduce pain, and 2) reduce inflammation. Though the mechanisms of this are still being studied, the inflammation reduction is thought to be a result of immune modulation, that is, telling the immune system causing the inflammation to calm down and return back to normal.

This in turn relieves associated pain, and is complimented by a further pain relief caused by the CBD directly that many consider to be more effective than opiates. The all-around action caused by a CBD bath bomb will induce benefits such as the following:

  • Inflammation due to injuries such as mosquito and spider bites, ingrown nails, and infections

  • Arthritic pain

  • Bodily tension

  • Sore muscles

  • Cramps and muscle spasm relief


6. Humidity

The humidity caused by the heat of the bath has twofold benefits: first, the warm mist is beneficial for the throat and lungs, and also, the humidity acts as a medium through which essential oils and CBD can travel into the body directly. This aids in aromatherapy.


7. Skin Care

Cannabis products, when applied to the skin, have been demonstrated to assist in a variety of skin ailments:

  • Anti-aging

  • Wrinkle reduction

  • Antioxidant effects

  • Eczema treatment

  • Psoriasis treatment

  • Acne and blackhead treatment


8. Essential Oils and CBD Compliment Each Other

When choosing your bath bomb, there is a great variety of essential oils to choose from. Each is associated with a different benefit, and when used in conjunction with CBD (the “ultimate” alternative medicine), the overlap can create powerful synergistic action. Below you’ll find a list of some of the more common essential oils, and their benefits:

  • Lavender – Associated with relaxation and serenity

  • Peppermint – Potent nausea relief

  • Eucalyptus Oil – Helps with breathing and immunity

  • Clove Oil – Treats arthritic pain and is antimicrobial

  • Grapefruit – Supports metabolism and kills cellulite

  • Frankicense – Builds immunity, neuroprotective

  • Cypress – Improves circulation

  • Ginger – Digestive aid and nausea relief

This opens the door to mood-based bath bombs and nearly unlimited experimentation with different products, a fun activity in its own right.


9. You Can Enjoy ALL The Benefits of CBD

The previously described increase in blood flow and pore opening causes the CBD to enter the bloodstream at a rapid pace. This means you’ll get all the same benefits of CBD taken another route, such as orally, plus more (you’d also get the topical benefits such as inflammation reduction). These major benefits include:

  • Nausea relief

  • General pain relief

  • Anti-seizure properties

  • Anxiety and stress relief

  • Insomnia treatment

  • Mood improvement

  • Neuroprotective properties

Stay tuned for Prevail’s signature, high potency, maximum relaxation CBD bath bombs coming soon*

CBD and Anxiety: Can it Really Help?

If you’ve been stressed lately, you’re not alone.

More Americans are stressed out than ever before. From tighter incomes to increased work pressures to a more divided political landscape to, of course, anguish over social media popularity, the pressure has become more than many of us can bear calmly.

Anxiety, it seems, has become a national epidemic.

In June of 2017, the New York Times featured a front-page article headlined “An Anxious Nation,” declaring that we have entered a troubling new “Age of Anxiety.”[1]

A year later, in August of 2018, the Washington Post repeated the claim, noting that a whopping 79% of Americans are frequently stressed.[2]

And it’s only getting worse.


Only Greeks are more anxiety-ridden than Americans

The American Psychiatric Association recently found in its annual mental health survey that “Americans’ anxiety levels experienced sharp increases in the past year.”[3]

That applies across all age groups. Fully 38% of teenage girls suffer with an anxiety disorder, and on college campuses anxiety is now more common than depression.

We are so afflicted that the 2019 Gallup World Emotions Report finds that only Greece suffers higher anxiety levels than the US.[4]


Anxiety drug prescriptions on the rise

Unsurprisingly, the number of prescriptions being written for anxiety drugs is also rising. CNBC reports a whopping 67% rise in prescriptions between 1996 and 2013.

What that huge increase means is that Americans, at around 5% of the world’s population, now consume 66% of the world’s psychological drugs. Think about it… a full 66% of the world’s psychological drugs. Let that sink in for a moment!

That increase has led to an unfortunate quadrupling of overdose deaths from anxiety drugs, including Xanax, Librium, Valium, and Ativan.[5]


It’s worth noting that so many people take Xanax that the drug generates more revenue than Tide detergent![6]


Those drugs account for an annual $3.3 billion in sales.

But do these drugs truly help?


Anxiety drugs fail up to half the time

Medications for the treatment of anxiety have become vastly less effective, and our tolerance to these drugs increases with continued use.

And that means over time, these prescription drugs do not do their job anymore.

In fact, a review published in the Journal of Anxiety Disorders in December of 2012 found that between one-third and one-half of all those who take anxiety medications fail to achieve remission of anxiety.[8]

The study’s authors ask, “Billions of research dollars later, have we hit a wall in the development and application of pharmacological treatments for anxiety?”

Lack of effectiveness isn’t the only problem, either. Benzodiazepine use is associated with addiction, cognitive impairment, psychomotor impairment, and rebound anxiety upon discontinuation.

Where antidepressants are prescribed for anxiety disorders, there is a 30–50% likelihood of side effects that include nausea, diarrhea, headache, insomnia, diminished sexual interest or performance, jitteriness, restlessness, and thoughts of suicide.

Clearly, there is an urgent need for better treatment options.

Says Esther Blessing of the New York University School of Medicine, “The substantial burden of anxiety-related disorders and the limitations of current treatments place a high priority on developing novel pharmaceutical treatments.”[9]

Cannabidiol, commonly known as CBD, may be the answer.

CBD is the active pain-relieving, non-psychoactive component of cannabis and hemp.

While cannabis-derived CBD is still not legal under Federal law, last year’s Farm Bill removed hemp-derived CBD from the Controlled Substances Act.


Strong evidence supports CBD to reduce even the worst anxiety

Word is getting around that taking CBD is a good way to relieve anxiety.

Surveys show that most people who take CBD do so to treat either chronic pain or anxiety.[10]

And they say it works, thank you very much.

Among one study of 2,409 CBD users, the vast majority of those who used CBD to relieve anxiety reported that it worked “very well.”[11]



Now the clinical evidence in support of CBD for anxiety is piling up too.

One of the most crippling forms of anxiety is social anxiety disorder (SAD). It imposes a constant angst about how others see you, worry about others’ disapproval, and fear of rejection. Sufferers feel locked in a cell of solitude, cut off from social contact.

Unfortunately, SAD is notoriously hard to treat.[12]

Yet CBD seems to unlock the cell of solitude for SAD sufferers, allowing them to finally feel the bond of human connection that was denied them.

One groundbreaking study published in Neuropsychopharmacology found that CBD significantly reduces anxiety, cognitive impairment, and social discomfort in subjects suffering from SAD.[13]

In the study, subjects with social anxiety disorder were asked to speak in front of a large audience. Half of them had been given a placebo, and half took CBD.

Researchers compared anxiety levels between the two groups and found that “people who took CBD reported significantly less anxiety” than those who got the placebo.

In another trial, subjects were given either CBD or a placebo. Researchers then took brain scans, as well as asked for a subjective reading on individual anxiety levels.

What they found was that “CBD was associated with significantly decreased subjective anxiety.”[14]

Other anxiety disorders are just as likely to be relieved with CBD use.

One 2015 review published in Neurotherapeutics found that “evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder.”[15]

The review concluded that “evidence indicates CBD has considerable potential as a treatment for multiple anxiety disorders.”


More and more doctors recommend CBD for anxiety

Virginia Thornley, a board-certified neurologist in Sarasota, Florida, says that CBD’s effects are similar to anti-anxiety medication or antidepressants.

Pritham Raj, an internist-psychiatrist in Portland, Oregon says that among cannabis components, “CBD is the best of all options in reducing anxiety.”

And Blake Pearson, a physician in Ontario, Canada says, “For those patients who have tried and failed with prescription anti-anxiety medications or want another option for other reasons, CBD is a potential alternative with a good safety profile that offers fewer negative side effects and fewer contraindications with other substances.”

More and more research is confirming CBD’s value in alleviating anxiety… More and more doctors are recommending CBD for anxiety… And more and more users are finding relief for both mild and acute anxiety with CBD.


[1] https://www.nytimes.com/2017/06/10/style/anxiety-is-the-new-depression-xanax.html

[2] https://www.washingtonpost.com/business/2018/08/02/an-anxious-nation-barnes-noble-sees-surge-sales-books-about-stress/?utm_term=.d2d257739f22

[3] https://www.psychiatry.org/newsroom/news-releases/americans-say-they-are-more-anxious-than-a-year-ago-baby-boomers-report-greatest-increase-in-anxiety

[4] https://www.psychologytoday.com/us/blog/shouldstorm/201904/us-leads-in-the-worldwide-anxiety-epidemic

[5] https://www.cnbc.com/2018/08/02/antianxiety-drugs-fuel-the-next-deadly-drug-crisis-in-us.html

[6] https://www.theguardian.com/commentisfree/cifamerica/2011/mar/15/psychology-healthcare

[7] https://www.cnbc.com/2018/08/02/antianxiety-drugs-fuel-the-next-deadly-drug-crisis-in-us.html

[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539724/

[9] https://link.springer.com/article/10.1007/s13311-015-0387-1

[10] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/

[11] Ibid

[12] https://oxfordmedicine.com/view/10.1093/med/9780199739981.001.1/med-9780199739981-chapter-0007

[13] https://www.nature.com/articles/npp20116?foxtrotcallback=true

[14] https://www.ncbi.nlm.nih.gov/pubmed/20829306

[15] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/

[16] https://seekingalpha.com/article/4264100-tilray-inc-tlry-ceo-brendan-kennedy-q1-2019-results-earnings-call-transcript

Compliments of: CYNTHIA BERRYMAN

Can CBD Heal Wounds?

Treating wounds and skin conditions with CBD topicals has been done through the millennia. They come in the form of lotions, balms, creams, oils or salves that are applied directly to the injury. The definition of injury in conjunction with these products can be cuts; lacerations; burns; puncture wounds; surgery and malignant wounds; injured muscles; or conditions such as arthritis, neuropathy, psoriasis. CBD is a versatile and effective wound treatment.

Research shows that CBD cannabis has strong analgesic, anti-inflammatory and antiseptic properties. The body’s endocannabinoid system, involved with the process of healing itself, is enhanced with the application of CBD topicals. Often healing can often occur more quickly with CBD than over-the-counter medicines.

In the case of a malignant wound, or an open cancerous skin lesion, which may be draining, a case report published in January 2017 in the Journal of Pain and Symptom Management suggests topical cannabis may aid in the treatment of such wounds. The report told of a 44-year-old man with a cancerous lesion on his cheek that had been treated with chemotherapy, surgery and radiation. All to no avail. He turned to CBD for pain relief and found that in addition to relieving his pain, the lesion began to heal.

CBD’s sterilizing properties protect the area while promoting skin cell growth, and even desensitizing your body to pain. It also sanitizes the wound providing antibacterial protection as the wound heals. CBD is especially helpful in treating burns. In addition to helping them heal faster, continued use keeps the burn clean, reduces pain and inflammation and may prevent scarring.

Athletes or those suffering from arthritis have found relief with CBD. Individuals, who because of illness or medical treatment find their skin feeling and looking dry and lifeless, have used CBD lotion to protect skin. In doing so, they find it also replenishes the skin.

How to Find the Right CBD Dose for You

If you suffer from insomnia, feel anxious, have chronic pain or have been diagnosed with any of a host of other ailments, you may have heard that “CBD is good for that.” But how DO you dose it exactly?

With a CBD salve, it’s as simple as applying to the area of pain, rubbing it in, and then letting it do it’s work. But what about CBD from oil tinctures?

Cannabidiol (CBD) is an extract from hemp flowers that is taking the health and beauty world by storm. Preliminary research suggests that because of its antiinflammatory and neuroprotective effects it may support those suffering from addictions, Alzheimers, concussion, fibromyalgia, diabetes, multiple sclerosis, sleep disorders and many other conditions. But this potentially useful supplement does not come with one-size-fits-all dosing recommendations. In fact, you will have to use a little trial and error to find your right dose. These guidelines will help you do just that.

Low and Slow

This will be your motto as you find your optimal CBD dose. As you begin, you should make sure you tolerate it well before working your way up to a dose that relieves your unique symptoms. This process is called microdosing or self-titration, both of which mean you are in charge of finding the lowest effective dose for you. 

Registered nurse and medical cannabis expert Eileen Konieczny, in her book, Healing with CBD, recommends starting with a microdose of 10 mg, or even dividing that into two or three doses in the course of a day. After a few days or a week at this level, she says, you can gradually increase the dose by five to 10 milligrams at a time. 

Konieczny and others recommend this process of slowly raising the dose while keeping notes on your symptoms in a journal so that you can monitor the extract’s effectiveness.

Know The Product

One of the challenges of finding the right dose for you is knowing exactly how much CBD is in the product you bought, and how much is in each dose of that product. Tinctures are ideal for microdosing because they allow you to slowly increase your dose in a way that edibles and capsules do not. Starting with a tincture, especially taking it sublingually (under the tongue), is a good way to understand how CBD affects you and what a good dose will be for you. 

Look on the product label for the total milligrams (mg) CBD in the container and per dose in the supplement facts table. Make sure you don’t get your units confused here: milliliters (ml) measure the volume of a liquid while milligrams tell you the weight of the extract that was dissolved into the liquid of the tincture. If you have purchased a tincture and feel like you’ve taken on the world’s worst math problem, this may help. 

● Most (though not all) tincture bottles are one ounce, or 30 milliliters (ml) 

● The standard dropper size is 1 ml 

● If your bottle contains 500 mg CBD, each dropper contains just under 17 mg extract 

● To start at 10 mg, you will need about 12 drops from that dropper 

You can increase by as little as one drop at a time as you self-titrate to find the “sweet spot” for you.

The Sweet Spot

The right dose gives you the effect you want using the lowest possible amount. At this dose you will start feeling the benefit from what you are taking, but are unlikely to experience any side effects (CBD has almost no reported adverse effects, however your results may vary). Taking the time to find this minimum effective dose, even with all the math and symptom tracking involved, also saves you money as you take only as much as you need.

Once you find a dose that feels like it’s working, bear in mind that your body is a dynamic system and changes in sensitivity may occur. Ongoing daily or intermittent symptom tracking will help you know when to adjust your dose.

Lastly, don’t hesitate to take a low dose of CBD for maintenance purposes. Integrative medicine practitioner and medical cannabis expert Dr. Dustin Sulak says doing this can be an effective long-term approach to healing. “Over time,” he says, “I began to notice that most patients using small amounts of cannabis were getting better and more sustainable results than their high-dosage counterparts with similar conditions.” 

By choosing a high-quality, clearly labeled product and using the microdosing approach experts recommend, you are giving yourself the best odds of experiencing a higher level of well-being with the support of CBD.

Can CBD Help to Lose Weight?

Some people believe that CBD can aid weight loss, but does it work?

There are many possible uses for CBD, from fighting acne to reducing anxiety. Researchers are also looking at the possibility that CBD can help people lose weight and reduce their risk of experiencing issues associated with weight, such as diabetes and metabolic disorder.

In this article, we discuss CBD for weight loss, including whether or not science backs up the hype.

CBD and weight loss

There is some evidence to suggest that taking CBD may help a person lose weight.

CBD may aid weight loss due to how it works in the body.

The body has a built-in endocannabinoid system. This system responds to different compounds in the body through two cannabinoid (CB) receptors, called the CB1 and CB2 receptors.

Usually, CB1 receptors exist mainly in the brain and central nervous system and are almost nonexistent in the rest of the body. CB2 receptors, on the other hand, exist throughout the body.

In people with obesity, however, CB1 receptors become more widespread, especially in fatty tissue. Because of this, researchers believe that there may be a link between the activation of the CB1 receptors and obesity.

CBD does not activate the CB receptors directly, instead influencing the body's natural cannabinoids to either block off or activate the receptors. This may play a role in weight loss or other critical metabolic functions.

There is some evidence to suggest that CBD can help a person lose weight or help prevent metabolic disorders.

Claims and research

Some people claim that CBD:

Reduces appetite

Many proponents say that the compound can help a person lose weight by reducing their appetite.

Most people associate cannabis with a stimulated appetite, as people who smoke cannabis tend to feel more hungry than usual. While it is true that tetrahydrocannabinol (THC), the psychoactive component of cannabis, may cause hunger, CBD does not.

THC activates the CB1 receptors in the body, causing many effects, including stimulating the appetite. However, as the authors of one 2018 study paper note, CB1 receptor antagonists may help reduce appetite and control obesity. This is because CB1 receptor agonists block off or "deactivate" the receptor.

CBD does not deactivate CB1 receptors but may influence other molecules to block them off. Shutting off these receptors may help reduce the appetite and prevent overeating in some people.

An older animal study from 2012 found that exposure to CBD reduced appetite in rats. While there is plenty of anecdotal evidence to suggest that CBD is helpful for appetite suppression, there have been no direct studies that show CBD reduces appetite in humans.

Turns bad fat into good fat

Proponents of CBD for weight loss also claim that it can convert white, or "bad," fat into brown fat, which may help the body burn calories.

White fat may also increase the risk of many chronic conditions, such as heart disease and diabetes.

2016 study helps back up this claim. The researchers found that CBD plays multiple roles in how the body interacts with fat.

Not only did CBD help convert white fat cells into brown fat cells, it also stimulated the body to break down fats more efficiently.

The researchers note that CBD may be a promising therapy for preventing obesity, but more studies in humans are necessary.

Burns fat

Another claim is that CBD melts away fat in the body by breaking down the fat and helping eliminate it from the body as waste.

Research from 2018 helps explain this phenomenon. The process of turning white fat cells to brown fat cells actually changes how these cells act in the body.

Brown fat cells may be a more active form of fat. They burn off energy as heat, meaning that they actually burn calories.

As a loss of calories is vital for weight loss, CBD may help burn fat if it turns white fat to brown fat in the body.

Reduces the risk of metabolic disorders

As other 2018 research notes, there is a close link between obesity and several metabolic disorders, such as type 2 diabetes, high blood pressure, and high cholesterol.

The overactivation of the CB receptors in the body may be partly responsible for this. Overactivation of the CB1 receptors in the fat tissue throughout the body could contribute to obesity and metabolic risks.

CBD helps block off the CB1 receptors, meaning that it might reduce the risk of obesity.

A review in Cannabis and Cannabinoid Research also notes some highlights of past studies surrounding CBD and metabolic factors, mainly in animal models.

For instance, a treatment using CBD reduced total cholesterol by 25 percent in obese rats. The anti-inflammatory and antioxidant effects of CBD also appeared to decrease blood sugar levels and increase markers for liver health.

Risks and considerations

Eating healthfully and exercising are important parts of any weight loss plan.

While initial results from studies on CBD and weight loss put forth some promising suggestions, there are a few important things to consider.

CBD, or any other compound, supplement, or drug, is not a treatment for obesity. These supplements and compounds do not replace a healthful diet and regular exercise.

A person who adds CBD to their weight loss plan without also exercising and eating healthfully may not see any benefits.

At best, people can consider CBD as a complementary therapy. Not all bodies are the same, and each person may need a slightly different dose.

Someone with more body weight or someone who regularly uses cannabis may need a higher dose, whereas someone who is very sensitive to cannabis or CBD may only need to take a very small amount for the compound to be effective.

It is best to work directly with a doctor when using CBD for weight loss. Doctors will want to discuss any other medications the person is taking, as CBD may cause adverse interactions.


The initial results of studies into CBD and weight loss are promising and may prompt more research into the connection between them.

CBD may be helpful for people looking to lose weight, burn calories, or suppress appetite, but it is vital not to overstate these claims.

A healthful diet and plenty of exercise are still the best weight loss strategies.

CBD should not replace any other medications a person is taking for chronic conditions. People should talk to a doctor before using CBD for any reason, as it may interact with their existing medications.

CBD is available for purchase in some health food stores, pharmacies, and online.

*Research kindly compiled by Medical News Today.

CBD for Inflammation

Inflammation occurs as a natural protective response when the body is harmed. There are two types of inflammation: acute and chronic. 

Acute inflammation occurs following an injury, infection, or illness. The immune system unleashes immune cells to the affected area to protect it, causing redness and swelling.

Chronic inflammation refers to a prolonged inflammatory response in the body. When inflammation lingers, it can detrimentally impact tissues and organs due to the increased production of free radicals, which result in oxidative stress.

Inflammation and oxidative stress are involved in many diseases. Chronic inflammation may be caused by autoimmune disorders, untreated infections or illnesses, and often plays a role in conditions such as asthma, cancer, and diabetes. Factors such as smoking, obesity, or stress may also contribute to chronic inflammation.

While inflammation is necessary to help protect the body as it heals, a state of ongoing or chronic inflammation is undesirable and can be a source of significant pain, anxiety, and is sometimes linked with depression. CBD has been touted as a potent plant-derived anti-inflammatory. Is there research to support its use in the treatment of acute and chronic inflammation?


Research has shown that CBD is able to modulate the immune system. While CBD does not have much affinity for the body’s cannabinoid receptors, CB1 and CB2, it does affect other receptors and targets. CBD binds to TRPV1 receptors and rapidly desensitizes them. TRPV1 receptors are known to mediate pain and sensory perception, inflammation, and body temperature.

CBD has been shown to reduce inflammatory pain in animal models, but again, not by interacting directly with the body’s cannabinoid receptors. Rather, CBD appears to block inflammatory pain by interacting with another protein, the glycine receptor, which plays a critical role in transmitting pain signals from the body, through the spinal cord, and into the brain (where pain is actually perceived).

CBD also acts on inflammation by decreasing oxidative stress in the body. Oxidative stress occurs when there is a disturbance between the production of free radicals and antioxidant defenses, resulting in inflammation or tissue damage. CBD possesses antioxidant properties, and has been shown to markedly reduce oxidative stress and inflammation in the body following a potent chemotherapy treatment.

The Studies on CBD Oil for the Treatment of Inflammation

A 2015 review published in Bioorganic and Medicinal Chemistry by Elsevier discussed the anti-inflammatory properties of CBD. The reviewers found that CBD reduces inflammation through several pathways in the body, and represents an effective potential treatment for a range of conditions characterized by inflammation.

A 2017 study in the journal Pain by publisher Lippincott, Williams, and Wilkins examined the effects of CBD in male rats with osteoarthritis. After two weeks, acute inflammation of the joints was reduced by local CBD treatment applied to the area. The administration of CBD was also found to prevent the development of nerve damage and joint pain.

A 2016 study published in Clinical Hemorheology and Microcirculation by IOS Press investigated CBD as a treatment for early pancreatic inflammation in diabetic mice. Pancreatic inflammation can lead to diabetes due to an invasion of immune cells that destroy insulin-producing cells. The mice who received 10 weeks of treatment with CBD developed diabetes later than the mice that didn’t receive the treatment, and also showed a significant reduction in leukocyte activation. Leukocytes are an immune cell. 

A 2011 study published in PLoS One explored the effects of CBD on acute and chronic inflammation in the gut. This elegant research was conducted on animal models with intestinal inflammation and biopsies of human patients with ulcerative colitis. CBD was found to profoundly counteract the inflammation, and also reduced intestinal damage in the mice and human biopsies by decreasing the expression of inflammatory proteins.

Patient Perspectives

Amy Orr, author of a forthcoming book, “Taming Chronic Pain,” has been using CBD oil for three years to treat the inflammation and pain associated with irritable bowel disease, an autoimmune illness. 

“I have had IBD for over 20 years, and had been on a range of medications, from steroids to opioids,” Orr said. “The steroids helped a lot with inflammation but not with the pain, and the oxy was like trying to crack a nut with a sledgehammer — brutal side effects. It made me feel awful due to bad nausea and extreme fogginess.”

Orr first experimented with medical marijuana with mixed results, then discovered CBD. “I’ve found more long-term success with fewer side effects from CBD oil,” Orr stated. 

“I’d say switching to CBD oil was like a ‘eureka’ moment for me, and I couldn’t really believe that something this good and simple hadn’t been available to me from the get-go.”

For Orr, CBD was immediately more effective that both opioids and steroids, and even better than edibles. “I’m able to titrate my dose very exactly, and can vary the amount depending on how bad a day I’m having.”

“I’ve had a variety of experiences with different doctors, as well as with different ingestion methods. However, I have genuinely found CBD oil to be transformational and am committed to increasing awareness for other autoimmune and IBD sufferers.”

Adam Kemp is a professional basketball player who turned to CBD products after breaking a bone in his back at the beginning of the 2017-2018 season. 

“I was able to undertake my whole recovery from the back injury by using only CBD products, and now I continue to use them to help with inflammation and other muscle pains,” Kemp said.

However, not everyone who has turned to CBD to help with their inflammation has experienced benefits. 

Lucy Blythe, whose name has been changed for this article, has experimented with CBD to help treat her chronic fatigue syndrome, Lyme disease, and fibromyalgia — all of which are autoimmune illnesses characterized by chronic inflammation in the body.

“I have taken CBD to fight inflammation and have tried four different brands,” Allen explained. “I didn’t notice a difference with any of the brands. So, I prefer to use my other anti-inflammatories, like Plaquinel, low-dose naltrexone, and turmeric.”

Medical Experts Weigh In

Jeremy Riggle, Ph.D. is a scientist in Colorado.

“Overall, the research literature indicates that cannabinoids, including CBD, could potentially be very effective anti-inflammatory agents for nervous tissue inflammation, inflammatory bowel disease, arthritis, vascular inflammation and certain types of cancers that are triggered by chronic inflammation,” Riggle said.

He cautions, however, that there is still a long way to go before scientists fully understand how CBD attenuates inflammation.

“Inflammation is an extremely complex and varied process, and the effect of CBD and other cannabinoids is not completely understood at this time,” Riggle explained. 

“What we do know is that cannabinoids exert their observed anti-inflammatory effect through induction of apoptosis (programmed death of abnormal or damaged cells), inhibition of cellular proliferation, suppression of cytokine production (proteins that regulate the inflammatory response), and induction of T-regulatory cells. 

Riggle emphasizes that the mechanisms by which CBD acts on the body, its specific applications, and appropriate doses require further study. That being said, Riggle acknowledges that CBD represents a low-risk, high-reward treatment for inflammation, as it is non-toxic and has minor side effects. 

Stacia Woodcock, a pharmacist at Curaleaf New York  points out that it may take some time for CBD oil to exert its anti-inflammatory effects on the body.

“Based on my experience, I think that CBD may offer some relief if dosed properly, such as a minimum of 50 milligrams a day to start, but it may take a few weeks to see a good result,” said Woodcock.

Wrap Up

Although there are many preliminary studies and animal studies, there still is a long way to go as clinical trials unfold. It’s always best to consult with your physician before starting any kind of new regime.

*Research compiled by Weedmaps

CBD & Arthritis

Arthritis is the one of the leading causes of disability in the United States, and it affects over 50 million Americans. The two most common types of arthritis are:

  • Rheumatoid arthritis (RA): An autoimmune disease in which a person's immune system attacks their joints, causing inflammation. RA commonly affects the hands and feet and leads to painful, swollen, and stiff joints.

  • Osteoarthritis (OA): A degenerative disease that affects joint cartilage and bones, causing pain and stiffness. It often affects the hip, knee, and thumb joints.

Some early studies on animals suggest that CBD could help to treat arthritis and relieve the associated inflammatory pain. There are also hundreds of testimonials from CBD users all over the world.

  • A 2011 study found that CBD helped to reduce inflammatory pain in rats by affecting the way that pain receptors respond to stimuli.

  • A 2014 review of the existing body of research on animals concluded that CBD may be an effective treatment for OA.

  • A 2016 study found that the topical application of CBD had the potential to relieve pain and inflammation associated with arthritis.

  • A 2017 study found that CBD might be a safe and useful treatment for OA joint pain.

For more targeted relief, those who suffer from arthritis might consider using a salve or balm to apply directly the painful areas as opposed to oil ingestion. The former has better absorption capabilities for the pain.

There still need to be more human studies completed on CBD and arthritis, but unfortunately the likely won’t take place until the U.S. government completely legalizes all form of cannabis at the federal level.

How Long Does It Take CBD to Actually Work?

So, you’ve heard about how CBD oil works wonders for chronic pain relief, anxiety, or for many other conditions. You finally sit down, unscrew the cap from the CBD oil bottle, and prepare to set out on a soothing journey guided by this non-intoxicating cannabinoid. After taking a few drops of CBD oil or applying a CBD-infused topical to the skin, you might start to ponder the following questions:

  • How long does it take for this stuff to work?

  • How long will the effects last?

Keep in mind, we still need a lot more clinical research before drawing certain conclusions, but we are getting closer.

How Does CBD Interact with your Body? 

Upon entering the system, CBD interacts with a wide range of proteins in the body and central nervous system. A key part of this interaction takes place within the endocannabinoid system (ECS), specifically affecting the CB1 and CB2 cannabinoid receptors. Unlike THC, which is the intoxicating cannabinoid that binds to these receptors and creates the stoned effect, CBD is actually an inverse agonist to the cannabinoid receptors. 

When cannabidiol is introduced to the ECS, it inhibits the absorption of anandamide, a natural cannabinoid molecule that regulates pain. The effect of CBD on the CB1 and CB2 receptors is indirect, as it increases levels of anandamide and 2-arachidonoylglycerol, the two most prevalent endocannabinoids in the body. Research has shown that CBD targets alpha-3 glycine receptors to suppress chronic pain and inflammation associated with dysfunctional glycine receptors, an important target for pain processing in the spine. 

CBD also interacts with other receptor proteins not directly related to the ECS, such as the serotonin receptor 5-HT1A and vanilloid receptor TRPV1. The widely perceived anti-inflammatory and pain relieving properties of CBD could stem from the activation of these additional biological pathways. 

The relationship between CBD and the human body is rather complicated, but it’s a bit easier to understand how this cannabinoid moves through the body, as well as how long it takes CBD to get out of your system. Even this answer, however, is contingent on several factors, including the method of consumption, the quality of the CBD product, as well as the person consuming.

How You Take It Matters

Method of consumption plays a critical role in how long it will take to feel the effects of CBD. CBD can be utilized in many different forms, and each has an influence on the onset time, among other factors. 


As the most common method for CBD consumption, administering a couple of drops directly into the mouth is the quickest and easiest way to reap the benefits of this therapeutic cannabinoid. But quickly swallowing the oil also prevents CBD from immediately entering the bloodstream, sending it instead through the digestive tract and eventually onto the liver, where it is broken down before finally reaching the bloodstream. 

This process can take awhile.

Studies show that when CBD compounds are metabolized by the liver, it undergoes what is called the “first pass effect,” where cytochrome P450 (CYP450) oxidases enzymes in the liver and reduce CBD concentration before the remainder is finally sent to the bloodstream and circulated throughout the body.

For ingestion of CBD edibles, the same principle applies. Let’s say, for example, you’re taking gummies or adding a few drops of CBD oil into your favorite recipe. It will ultimately go through the same lengthy process and reduce the total CBD concentration found in plasma. With ingestion, it could be one to two hours before the effects of CBD finally set in. 


CBD oil can be consumed sublingually by placing a few drops of CBD under the tongue before swallowing. By using this method, CBD is absorbed by the mucous membranes located in the mouth, bypassing the digestive system and liver. Compared with ingestion, this process allows the consumer to skip over the initial metabolization process, where CBD molecules are broken down in the liver, allowing it to enter the bloodstream sooner than ingestion.  


Whether you’re smoking a high-CBD strain or taking a draw from a CBD vape pen, inhalation is often seen as an effective method of delivery for CBD because of how quickly it’s absorbed in the body. When CBD is smoked or vaped, cannabinoids are sent directly to the lungs, where they are rapidly absorbed into the bloodstream and put into circulation throughout the body. It reaches peak concentrations in plasma within 3 minutes after consumption, meaning the effects can be felt shortly after use. 


Topical CBD is applied directly to the skin and can be absorbed through the surface of the skin to interact with localized cannabinoid receptors. In some cases, CBD-infused topicals (such as Prevail Salve) should be applied liberally to overcome the low cannabinoid absorption rate of the skin, allowing CBD to pass through the skin via the pores. When CBD is applied topically to the skin, the permeability of CBD is tenfold higher than THC, and peaks after 90 minutes. This method of administration is ideal for dealing with chronic pain in specific areas. 

You and Your CBD Dosage

The way CBD operates throughout the body – and is inevitably excreted from the body – also depends on several factors that vary from person to person. 

Body Weight 

The amount of body fat will influence the amount of CBD that would be deemed effective. Someone with a larger body mass will require more CBD in order to feel the effects. Body weight and mass also affect on how long the CBD remains in the system. Like THC, CBD is stored in the fat cells and gradually eliminated from the body through urine and feces. Does CBD have to build up in your system to work effectively? No, but it does get stored in the fat cells and can remain in the body well after the effects of CBD diminish. 


The metabolic rate of the individual also has some sway over how long CBD stays in the system. The body’s metabolism determines how long it takes to break down and synthesize compounds, which will affect how long it takes the body to process and metabolize the cannabinoid. 


It’s not just the human body that influences how long it takes CBD to work, but also the quality of the CBD product and how often it’s used. Once the CBD oil is acquired, the next step is to find the optimal dosing regimen, including frequency of use. Perhaps you’ve wondered to yourself:

  • Should I take CBD oil in the morning or at night?

  • What’s the right time of day to take CBD?

The answers will depend largely on the type of product, amount of CBD inside of it, and the specific ailment that you are targeting. Most reputable manufacturers will provide instructions on how to properly utilize the product, but experimentation may be required to find the optimal dose for each individual and their specific needs.

CBD Dosage 

Settling on the ideal CBD dosage is an important part of the treatment process, and will also impact how long CBD stays in your system.  

Hemp-derived CBD products are not intended to give the user a stoned buzz or intoxicated feeling, so there’s no need to be conservative with the dosage amount. Still, it’s recommended to start with a lower dosage and gradually increase it until the ideal effects are discovered.  

How Long Does it Take CBD to Get Out of Your System? 

We’ve covered the factors that determine how long it takes for CBD to work, but what about how long it takes to get CBD out of your system? Again, it depends on many of the aforementioned factors that determine the effectiveness of the cannabinoid itself. 

2007 study states that CBD can be detected up to 72 hours after smoking. Since the effects of CBD can be felt directly after inhalation, this method is appealing for those seeking immediate pain relief. In another study, volunteers were given soft-gelatin capsules containing cannabis extract containing 2.5 milligrams of THC and 1.35 milligrams of CBD. The research team found that CBD was only detectable in the blood for up to 360 minutes after ingestion.  

Some people may be apprehensive to try CBD over concerns that it could cause them to fail a drug test. It’s highly unlikely that CBD would show up on most drug screenings, as most tests specifically look for the presence of THC and THC metabolites. But even hemp-derived CBD can contain trace amounts of THC, so there’s technically a chance, albeit extremely slim, of receiving a false positive test result from taking an unusually large dose (estimates range from 1,000 to 2,000 milligrams per day) of CBD oil. 

For those worried about THC showing up in their system, look for broad-spectrum oil or products that contain pure CBD isolate. Broad-spectrum oil, as opposed to full spectrum oil, is refined to exclude the trace amounts of THC that may have been present in the hemp plant. Products with CBD isolate contain no THC or other plant-based cannabinoids. To find high-quality CBD, search for products that come with a certificate of analysis from a third-party testing lab to ensure that the information listed on the product label is accurate. Also, be on the lookout for products that claim to be hemp seed oil or hemp oil, which seldom contains any CBD at all. 

**Thank you to Weedmaps for the date compiled in this article.

This 1 Botanical Changed My Life (How Prevail was Born)

In 2016 I started running mountains. I had just “retired” from elite mountain bike racing and started finding a newfound love to scaling the peaks around Salt Lake City, UT where I lived at the time. The addiction to running these peaks was real, and so was my addiction to ibuprofen.

It’s what my mom did. I mean, after all, she had 3 knee surgeries in her life and I watch her take ibuprofen assuming it was helping the swelling and inflammation, so why not follow her lead?

I had been cycling for over 15 years at a high level, and never really experience the banging of the knees as I came down these massive peaks. So as the pain and swelling set in each night, I would turn to ibuprofen. It got so bad, that I was actually taking 6 pills in the morning, and another 6 at night. I kept running mountains. The pain kept coming back and so finally after being so incredibly frustrated, I started looking into alternative medicines, plants, and other natural anti-inflammatories.

Deep in my search, I had heard of cannabis as being touted as a plant that had medicinal benefits, despite the emerging legal status of the plant in so many parts of the U.S. When I traveled to Colorado, I went into a dispensary and bought a cannabis topical cream that I could rub directly onto my sore legs. The cream was ok, but still not the result I was hoping for and it was quite expensive. I continued to research cannabis more, proper dosages, delivery methods, and I ended up learning about CBD or cannabidiol. I learned that cannabidiol was one of over 100 cannabinoids that are contained in the cannabis plant. CBD happened to be one of the power houses for reducing inflammation, but without the “high” effect of the plant typically desired by recreational users.

So for the better part of a year, I tried nearly 100 different CBD products. Most were the same junky product made in the same factories, and a few were reasonably effective, but nothing really truly was reducing the inflammation if I was being dead honest with myself. I wasn’t after a placebo, I wanted something that really worked-even after the most brutal 7 hour days in the mountains.

Since nothing really worked that well, I decided to seek out how to create my own. I needed purity in the CBD that was unsurpassed and extracted cleanly, more potency (basically just more full spectrum CBD per mg) and also other natural essential oils and botanicals which also had anti-inflammatory properties. After an arduous search, I finally found a wonderful manufacturer out of Boulder that worked with me to customize the formula just right. We changed it 3x, then finally dialed it in. Prevail was born.

It worked on my own sore and achy legs better than anything I had ever tried, but would it work for others? My gut said yes, but the testimonials that have flowed in since that time have blown my mind. Runners with gnarly fractures, sprained ankles, pulled or torn muscles, cramps, shin splints, and virtually every other running related injury were posting and writing about it on social media. Some would feel the effects in less than 5 minutes, some a few hours, and worst case scenario some just woke up the next morning feeling better.

Seeing people run, power-hike, ski, walk, or ride their bikes again with less or no pain has been the very thing that drives me each day. Getting out into nature and pushing our limits is what this sport is all about, and being able to enjoy it just a little bit more through something natural is amazing. I just want people to go further, train harder, recover faster, and as a result of feeling good-enjoy life more. That’s what our mission is really all about.

Brock Cannon Comment